Superman could regenerate physical damage to his body at an accelerated rate. This ability was greatly aided by direct sunlight exposure.

He was able to completely regenerate when his throat was slit, as well as when his body was reduced to near a skeleton by a special nuke. When injured by Kryptonite weapons, his healing Factor is usually deactivated by the mineral. Once the Kryptonite is removed or move far enough away, the wounds heal almost instantaneously. If his exposure to Kryptonite is prolonged enough, it might take longer for the injuries to heal.