River Song

Professor
Doctor (PhD)

Melody Pond
Mels Zucker
River Song

Proto-Time Lord

Demons Run, Asteroid

Amy Pond (Mother)
Rory Williams (Father)

The Doctor (Husband)

52nd Century

Died saving the Doctor, in the library
He uploaded her consciousness into a computer

Archaeologist

Conceived aboard the Doctor's TARDIS, gained some Time Lord DNA
Captured by The Silence, turned into a weapon to kill the Doctor
Became Mels Zimmerman, Amy & Rory’s best friend
Regenerates into River Song tried to kill the Doctor but ended up saving him
Imprisoned for killing the Doctor, freed when he erased all traces of his existence
Shared a long-lasting relationship with multiple incarnations of the Doctor

Alex Kingston (Doctor Who)