Borg Queen

Assimilated from Species 125 around the age of 7-8, along with her parents
2367: Part of the Battle of Wolf 359, the Cube she was on was destroyed
2373: Present when the Borg again attempted to assimilate Earth, body was destroyed
2375: Tried to assimilate Seven of Nine again, her vessel was destroyed
2376: Attempted but failed to crush an insurrection based out of "Unimatrix Zero"
2378: Inflected by a pathogen, which severed her link to the collective
Managed to survive by cannibalizing parts of her drones, driven insane
2401: Set in motion a plan to assimilate Starfleet from within;
Defeated which ended the Borg treat once and for all