A cargo bay or cargo hold is a general purpose storage facility aboard shuttles, starships and starbases. Cargo bays are often equipped with large transporters to assist in the moving of cargo containers. In emergencies, Cargo Bays would often be converted into triage areas.

The USS Voyager had several bays. One had variable environmental controls and was designed for organic storage. It was converted to a hydroponics bay/airponics bay by Kes in 2371 in order to allow for the growth of foods for consumption. In 2374, the Borg assimilated a Cargo Bay 2 during an alliance with Voyager. After the alliance, four Borg alcoves remained in the bay.