Goofy Goof was born in 1950, as the son of Amos Goof, in the town of Spoonerville. He once went to a trip to Yosemite with his father Amos, who taught him how to open a soup can with his bare teeth. As a child, he became best friends with Peter Pete, and the two attended the same high school.

He attended college in the 1970s but dropped out, before completing his final years, thus not getting a degree. Before going to college, his father Amos, gave Goofy an old typewriter. He got married in the late 1970s. The two moved out of Spoonerville, and later had a son named Max Goof in 1981. Mrs. Goof died sometime before 1991.

In 1991, Goofy and Max left their trailer park home to live in Goofy's hometown Spoonerville where they ended up living next door to Goofy's high school friend Pete, his wife Peg, their son P.J., and their daughter Pistol. By 1995, Goofy along with Pete worked as a children's photographer.

He is clumsy, and often cries out "Yaaaaaaa-hoo-hoo-hoo-hooey!", whenever he is falling in the air. Living a rather simple lifestyle, Goofy tends to miss the obvious, act somewhat childish and absent-minded, and gets confused very easily. As a result of these factors, Goofy is rather accident-prone and is an easy target for trouble. Nevertheless, his blissfulness usually keeps him from any legitimate harm, as he tends to walk away from life-threatening danger with a smile and his signature guffaw.

Goofy is extremely supportive and caring towards his loved ones. He tries his best to lighten their spirits when they feel down and selflessly sticks by them when they're in need. Goofy is also charming, somewhat infectiously; often at times when someone meets him for the first time, they are immediately taken by his welcoming aura.