Red Kryptonite is a mineral from the planet Krypton that removes inhibitions from super-powered Kryptonians making them reckless, evil, and dangerous.

This Kryptonite brings out the rebellious and immoral personality of Kryptonians and rids them of their inhibitions. The effects of Red Kryptonite are likened to that of being under the influence of too much alcohol or narcotics, without the loss of physical capability. In addition, Red Kryptonite appears to have no detrimental physical effects on health or the functioning of powers.

Red Kryptonite gives off radiation similar to its green counterpart. It does not usually infect humans, unless it enters their bloodstream.

The effects of Red Kryptonite are immediately countered by distance.